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Generic name: Quinsul, Quinate, Novo-Quinine, Apo-Quinine, Aethylcarbonis Chinin, Quinbisu, Kinin, Genin, Quininga, Quinine-Odan, Circonyl, Quinimax, Q300, Qualaquin, Quinarsal, Q200

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Quinine is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk. In doses several times higher than those used to treat malaria, quinine may stimulate the pregnant uterus. A manufacturer of a formerly available quinine product considered it contraindicated in pregnancy. Quinine is approved for treatment of malaria, but is also commonly prescribed to treat leg cramps and similar conditions. Because malaria is life-threatening, the risks associated with quinine use are justified for that condition. However, there is only one quinine product approved by the FDA. The FDA-approved labeling for the product provides extensive warnings regarding serious adverse events associated with use of quinine, potentially serious interactions with other drugs, and conditions under which quinine should not be used. The development of more effective alternatives such as quinacrine, chloroquine, and primaquine in the twentieth century reduced the reliance on quinine.

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